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Product introduction
甲硫噻平是一种二苯并噻平,是在10,11-二氢二苯并[b,f]噻平的基础上,在8位和10位分别带有额外的甲硫基和4-甲基哌嗪-1-基取代基。强效5-HT2拮抗剂,也作为5-HT1拮抗剂活性。区分5-HT1D亚型。还显示对啮齿动物5-HT5B、5-HT5A、5-HT7和5-HT6受体的亲和力(pK1值分别为6.6、7.0、8.4和8.7)。它具有抗衰老剂、抗精神病药、血清素能拮抗剂和多巴胺能拮抗剂的作用。它是一种芳基硫化物、二苯并噻平、N-烷基哌嗪和三级胺化合物。它是甲硫噻平(2+)的共轭碱。
Chinese name
methiothepin, 5-HT 1A 受体拮抗剂
English name
1-methyl-4-(3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine
Chinese alias
-
English alias
CCG-204888 | MLS000859918 | Spectrum4_001092 | EN300-2010375 | SPBio_002450 | Spectrum2_001967 | L000397 | 1-methyl-4-[6-(methylsulfanyl)-2-thiatricyclo[9.4.0.0,3,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-9-yl]piperazine | AB00053700 | KBioGR_001504 | METIT
CAS number
20229-30-5
molecular formula
C20H24N2S2
molecular weight
356.6
Exact mass
-
PSA
57.1
Logp
4.2
Safety
  • Hazard categories and classifications: STOT SE 3 (100%)
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methiothepin, 5-HT 1A receptorantagonist; 5-HT 1B receptorantagonist; 5-HT 1D receptorantagonist; 5-HT 1E receptorantagonist; 5-HT 1F receptorantagonist; 5-HT 2A receptorantagonist; 5-HT 2B receptorantagonist; 5-HT 2C receptorantagonist; 5-HT 5A receptorantagonist; 5-HT 6 receptorantagonist; 5-HT 7 receptorantagonist 5mg

methiothepin, 5-HT 1A receptorantagonist; 5-HT 1B receptorantagonist; 5-HT 1D receptorantagonist; 5-HT 1E receptorantagonist; 5-HT 1F receptorantagonist; 5-HT 2A receptorantagonist; 5-HT 2B receptorantagonist; 5-HT 2C receptorantagonist; 5-HT 5A receptorantagonist; 5-HT 6 receptorantagonist; 5-HT 7 receptorantagonist 5mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 5mg.

item number:M611817-5mg
Product model:5mg
level: 5mg
Lead Time:30days
sold 523 Items
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Specifications:

5mg

Qty

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