- Harmful effect： 美西律带有黑框警告，与1989年发表的"心律失常抑制试验"(CAST)的发现有关，该试验显示，在心肌梗死后患者中，抑制无症状、非危及生命的室性心律失常导致死亡率高于安慰剂组。尽管该研究使用Ic类抗心律失常药物进行抑制，但结果适用于所有I类抗心律失常药物。
- Toxicity summary： 美西律毒性的管理采用对症治疗。毫无疑问，当出现毒性时应立即停用美西律。根据毒性的严重程度，患者可能需要侵入性疗法来清除药物，如血液透析或血液灌流。Denaro在1989年发表的一篇论文指出，除了在有条件的情况下使用体外循环辅助外，这些干预措施也可能发挥作用。无论如何，患者应得到支持治疗，直到药物毒性作用消退。
- Regulatory information： REACH注册物质：状态：活跃 更新：2017-05-19 https://echa.europa.eu/registration-dossier/-/registered-dossier/19656
- Hepatotoxicity： 可能性评分：C（可能是引起明显肝损伤的罕见原因）。
- Hazard categories and classifications： 急性毒性 4 (100%)
- Drug Induced Liver Injury： 参考文献：DOI:10.1016/j.drudis.2019.09.022
- Effects During Pregnancy and Lactation： 截至修订日期，未找到相关已发表信息。
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mexiletine 5mg
mexiletine 5mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 5mg.
