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Product details

名称

MF-094

分子类型

未知

英文名称

MF-094

货号

M647943-5mg

包装规格

5mg

浓度

≥99%

储存温度

-20°C储存

运输条件

超低温冰袋运输

产品介绍

MF-094 is a potent and selective USP30 inhibitor with an IC 50 of 120 nM. MF-094 increases protein ubiquitination and accelerates mitophagy In Vitro MF-094 has Form:Solid IC50& Target:IC50: 120 nM (USP30)

生化机理

MF-094 是一种强效的选择性 USP30 抑制剂，IC50 为 120 nM。MF-094 可增加蛋白质泛素化并加速有丝分裂。

CAS号

2241025-68-1

分子式

C30H37N3O4S

分子量

535.70 g/mol

PubChem编号

138319686

Isomeric SMILES

CC(C)(C)NS(=O)(=O)C1=CC=CC2=C1C=CC=C2NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)C4CCCCC4

IIUPAC Name

N-[(2S)-1-[[5-(tert-butylsulfamoyl)naphthalen-1-yl]amino]-1-oxo-3-phenylpropan-2-yl]cyclohexanecarboxamide

INCHI

1S/C30H37N3O4S/c1-30(2,3)33-38(36,37)27-19-11-16-23-24(27)17-10-18-25(23)31-29(35)26(20-21-12-6-4-7-13-21)32-28(34)22-14-8-5-9-15-22/h4,6-7,10-13,16-19,22,26,33H,5,8-9,14-15,20H2,1-3H3,(H,31,35)(H,32,34)/t26-/m0/s1

InChi Key

DQXORJHBZHLLTE-SANMLTNESA-N

Smiles

CC(C)(C)NS(=O)(=O)C1=CC=CC2=C1C=CC=C2NC(=O)C(CC3=CC=CC=C3)NC(=O)C4CCCCC4

PubChem CID

138319686

MeSH Entry Terms

MF-094;N-((2S)-1-((5-(tert-butylsulfamoyl)naphthalen-1-yl)amino)-1-oxo-3-phenylpropan-2-yl)cyclohexanecarboxamide

溶解性

DMSO : 125 mg/mL (233.34 mM; Need ultrasonic)

氢键供体数Hydrogen Bond Donor Count

氢键受体数Hydrogen Bond Acceptor Count

可旋转键计数Rotatable Bond Count

精确质量Exact Mass

535.25 Da

单同位素质量Monoisotopic Mass

535.25 Da

拓扑极表面积Topological Polar Surface Area

113.000 Å²

重原子数Heavy Atom Count

形式电荷Formal Charge

复杂度Complexity

897.000

同位素原子数Isotope Atom Count

共价键合单元计数Covalently-Bonded Unit Count

XLogP3

5.700

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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