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名称

MEK inhibitor

别名

MEK 抑制剂

英文名称

MEK inhibitor

货号

M648999-5mg

包装规格

5mg

浓度

≥98%

储存温度

-20°C储存

运输条件

超低温冰袋运输

产品介绍

MEK inhibitor is a potent MEK inhibitor with antitumor potency. In Vitro MEK inhibitor is a potent MEK inhibitor. MEK is a kinase enzyme which phosphorylates MAPKs. The activated MAPK leads to the phosphorylation of downstream transcription factors that regulate various responses such as stress signaling, pathogen response, and hormone signaling. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:MEK

生化机理

MEK 抑制剂是一种强效 MEK 抑制剂，具有抗肿瘤作用。

CAS号

334951-92-7

分子式

C26H26N4O2

分子量

426.51 g/mol

PubChem编号

135742497

Isomeric SMILES

CNC(=O)C1=CC2=C(C=C1)C(=C(N2)O)C(=NC3=CC=CC(=C3)CN(C)C)C4=CC=CC=C4

Smiles

CNC(=O)C1=CC2=C(C=C1)C(=C(N2)O)C(=NC3=CC=CC(=C3)CN(C)C)C4=CC=CC=C4

PubChem CID

135742497

溶解性

DMSO : 50 mg/mL (117.23 mM; Need ultrasonic)

氢键供体数Hydrogen Bond Donor Count

氢键受体数Hydrogen Bond Acceptor Count

可旋转键计数Rotatable Bond Count

精确质量Exact Mass

426.206 Da

单同位素质量Monoisotopic Mass

426.206 Da

拓扑极表面积Topological Polar Surface Area

80.700 Å²

重原子数Heavy Atom Count

形式电荷Formal Charge

复杂度Complexity

660.000

同位素原子数Isotope Atom Count

共价键合单元计数Covalently-Bonded Unit Count

XLogP3

4.300

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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