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Product details

名称

ML148

分子类型

小分子

英文名称

ML148

货号

M654864-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

-80℃储存

运输条件

超低温冰袋运输

产品介绍

ML148 is a potent and selective 15-PGDH inhibitor with an IC 50 of 56 nM. ML148 has the potential for the research of prostaglandin-signaling pathways In Vitro ML148 (compound 13) shows selectivity with IC 50 s of 56, 36000, >57500, >57500 nM for 15-PGDH, ALDH1A1, HADH2, HSD17β4, respectively. ML148 (10, 20 nM) decrease V max by 25% and reduces the apparent K m by half at a concentration of 10 nM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:IC 50 : 56 nM (15-PGDH)

生化机理

ML148 是一种强效的选择性 15-PGDH 抑制剂，其 IC 50 为 56 nM。ML148 具有研究前列腺素信号通路的潜力。

CAS号

451496-96-1(DMSO)

分子式

C20H21N3O

分子量

319.4 g/mol

Smiles

CC1=CC(=CC=C1)N2C=NC3=C2C=CC(=C3)C(=O)N4CCCCC4

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

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