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Product details

名称

(S)-Mapracorat

别名

(S)-马普拉科拉

英文名称

(S)-Mapracorat

货号

M656357-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

-80℃储存

运输条件

超低温冰袋运输

产品介绍

(S)-Mapracorat is a selective and less active glucocorticoid receptor agonist. In Vitro (S)-Mapracorat concentration dependently inhibited TNFα secretion from activated canine PBMC with IC 50 value of approximately 0.2 nM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo Intradermal injection of compound 48/80 (50 μg in 50 μL saline) resulted in a clear wheal and flare reaction over the 60 min observation period. Topical pre-treatment with (S)-Mapracorat (0.1%) leads to significant reduction in the wheal and flare responses compared to vehicle (acetone) treated areas. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

生化机理

(S)-Mapracorat 是一种选择性和活性较低的糖皮质激素受体激动剂。

CAS号

887375-15-7(DMSO)

分子式

C25H26F4N2O2

分子量

462.48 g/mol

Smiles

CC1=NC2=C(C=C1)C(=CC=C2)NCC(CC(C)(C)C3=CC(=CC4=C3OCC4)F)(C(F)(F)F)O

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

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