ML-109

小分子

ML-109

M656637-1ml

1ml

10mM in DMSO

-80℃储存

超低温冰袋运输

ML-109 is a potent and full thyroid stimulating hormone receptor (TSHR) agonist, with an EC 50 of 40 nM. In Vitro ML-109 (Compound 2) is a full agonist at TSHR with an EC 50 of 40 nM and, like compound 1, it has no activity at FSHR or LHCGR. ML-109 contains an aminal, a functional group that is subject to hydrolysis and/or other degradation mechanisms. ML-109 is surprisingly stable at neutral and basic conditions (t 1/2 of ~16 h) but is found to degrade at low pH (t 1/2 of ~3 h). MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:EC50: 40 nM (TSHR)

ML-109 是一种强效、全面的促甲状腺激素受体（TSHR）激动剂，EC 50 为 40 nM。

1186649-91-1(DMSO)

C31H29N3O5

523.58 g/mol

CC(=O)NC1=CC=C(C=C1)OCC2=C(C=CC(=C2)C3NC4=C(C(=CC=C4)O)C(=O)N3CC5=CC=CC=C5)OC