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Product introduction
MP7 (PDK1 inhibitor) is a phosphoinositide-dependent kinase-1 ( PDK1 ) inhibitor. In Vitro Cell counting of U87MG-derived glioma stem cells (GSCs) confirms that Alisertib and, to a minor extent, MP7 (PDK1 inhibitor) are able to decrease the number of viable cells. When combined together, GSC viability is further reduced with respect to single-treated cells. As observed in U87MG cells, when used at the highest concentrations (i.e., 1.5 μM Alisertib and 2.5 μM MP7), a significant enhancement in the number of dead cells is evidenced. Following 72 h treatment, MP7 alone does not show a significant inhibition of glioblastoma multiforme (GBM) proliferation. MP7 has been shown to have only minimal effects on monolayer cell growth in several cancer cell lines, with IC 50 values in the micromolar range. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:PDK1
Chinese name
MP7
English name
MP7
Chinese alias
-
English alias
DTXSID90678515 | 1-(3,4-Difluorobenzyl)-2-Oxo-N-{(1r)-2-[(2-Oxo-2,3-Dihydro-1h-Benzimidazol-5-Yl)oxy]-1-Phenylethyl}-1,2-Dihydropyridine-3-Carboxamide | BRD-K09186807-001-01-6 | CHEBI:91373 | HY-14440 | PDK1 inhibitor | BDBM50361645 | NCGC00346947-02 | SC
CAS number
1001409-50-2
molecular formula
C28H22F2N4O4
molecular weight
516.50 g/mol
Exact mass
≥99%
PSA
99.800 Ų
Logp
4
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MP7 1ml

MP7 1ml; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 1ml.

item number:M656792-1ml
Product model:1ml
level: 1ml
Lead Time:30days
sold 840 Items
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Specifications:

1ml

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