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Product details

名称

ML 2-14

英文名称

ML 2-14

货号

M658700-5mg

包装规格

5mg

浓度

≥99%

储存温度

-20°C储存

运输条件

超低温冰袋运输

产品介绍

ML 2-14 is a PROTAC for degrading BRD4 , with C4 alkyl linker. ML 2-14 exerts degradation of BRD4 in 231MFP breast cancer cells. Appearance:Solid In Vitro:ML 2-14 with C4 alkyl linker showes robust degradation of BRD4 in 231MFP breast cancer cells, with DC 50 values of 36 and 14 nM for the long and short isoforms of BRD4, respectively. MCE has not independently confirmed the accuracy of these methods. Biological Activity:ML 2-14 is a PROTAC for degrading BRD4 , with C4 alkyl linker. ML 2-14 exerts degradation of BRD4 in 231MFP breast cancer cells.

分子式

C40H38BrCl2N7O3S

分子量

847.65 g/mol

Smiles

ClC1=CC=C(C=C1)C2=N[C@@H](CC(NCCCCOC3=CC=C(C4CC(C5=CC=C(Br)C=C5)=NN4C(CCl)=O)C=C3)=O)C6=NN=C(C)N6C7=C2C(C)=C(C)S7

溶解性

DMSO : 100 mg/mL (117.97 mM; Need ultrasonic)

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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