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名称

MMG-11 quarterhydrate

别名

MMG-11四分之一水合物

英文名称

MMG-11 quarterhydrate

货号

M658762-10mg

包装规格

10mg

浓度

≥99%

储存温度

-20°C储存

运输条件

超低温冰袋运输

产品介绍

MMG-11 quarterhydrate is a potent and selective human TLR2 antagonist with low cytotoxicity. MMG-11 quarterhydrate inhibits both TLR2/1 and TLR2/6 signaling with IC 50 s of 1.7 µM for Pam 3 CSK 4 -induced hTLR2/1 and 5.7 µM for Pam 2 CSK 4 -induced hTLR2/ Appearance:Solid IC50& Target:TLR2 In Vitro:MMG-11 neither shows cellular toxicity nor interference with signaling induced by other TLR agonists, IL-1β or TNF. MMG-11 (0.01-100 µM) shows no cytotoxic effects up to 100 µM in peripheral blood mononuclear cells (PBMCs). MCE has not independently Biological Activity:MMG-11 quarterhydrate is a potent and selective human TLR2 antagonist with low cytotoxicity. MMG-11 quarterhydrate inhibits both TLR2/1 and TLR2/6 signaling with IC 50 s of 1.7u202fµM for Pam 3 CSK 4 -induced hTLR2/1 and 5.7u202fµM for Pam 2 CSK 4 -induce

分子式

C15H14O7.1/4H2O

分子量

310.78 g/mol

Smiles

OC1=C(O)C(O)=C(C(CC2=CC=C(C(OCC)=O)O2)=O)C=C1.[1/4].O

溶解性

DMSO : 100 mg/mL (321.77 mM; Need ultrasonic)

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

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