Share to

Details

Safety

Technical Documents

Articles

reviews

Consult

returns

Product details

名称

Murepavadin TFA

别名

莫瑞伐定三氟乙酸盐 | 莫替尼

英文别名

POL7080 TFA

英文名称

Murepavadin TFA

货号

M659012-5mg

包装规格

5mg

浓度

≥99%

储存温度

-20°C储存,充氩

运输条件

超低温冰袋运输

敏感性

对湿度敏感

产品介绍

多肽序列：Cyclo(AS-{d-Pro}-PTWI-{Dab}-{Orn}-{d-Dab}-{Dab}-W-{Dab}-{Dab}) Murepavadin (POL7080) (TFA), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic . Murepavadin exhibits a potent antimicrobial activity for P. aeruginosa with MIC 50 and MIC 90 values both of 0.12 mg/L. Murepavadin also can target the Appearance:Solid IC50& Target:MIC50: 0.12 mg/L( P. aeruginosa ) MIC90: 0.12 mg/L( P. aeruginosa ) IC50: 5.84 μM (gentamicin) In Vitro:Murepavadin has activity against P. aeruginosa with MIC 50 and MIC 90 values both of 0.12 mg/L. Murepavadin inhibits megalin-mediated uptake of gentamicin in vitro with an IC 50 value of 5.84 μM. MCE has not independently confirmed the accura In Vivo:Murepavadin (s.c.; 0-10mg/kg) is active in pre-clinical animal models including infections with XDR isolates. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Murine models of P. aeruginos Biological Activity:Murepavadin (POL7080) (TFA), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic . Murepavadin exhibits a potent antimicrobial activity for P. aeruginosa with MIC 50 and MIC 90 values both of 0.12 mg/L. Murepavadin also can target the

CAS号

944252-63-5(free base)

分子式

C73H112N22O16(free base)

分子量

1553.837(free base) g/mol

溶解性

H2O : 50 mg/mL (29.98 mM; Need ultrasonic)

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

Warm reminder：

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！