Share to

Details

Safety

Technical Documents

Articles

reviews

Consult

returns

Product details

名称

MS117

英文名称

MS117

货号

M659445-5mg

包装规格

5mg

浓度

≥98%

储存温度

-20°C储存

运输条件

超低温冰袋运输

产品介绍

MS117 is a first-in-class and cell-active irreversible protein arginine methyltransferase 6 (PRMT6) covalent inhibitor, with an IC 50 of 18 nM. Appearance:Solid IC50& Target:IC50: 18 nM (PRMT6), 100 nM (PRMT1), 110 nM (PRMT8), 3 μM (PRMT3), 4 μM (PRMT4) . In Vitro:MS117 (Compound 4) inhibits the PRMT6 methyltransferase activity in a time-dependent manner. MS117 (Compound 4) shows moderate selectivity (6-fold) for PRMT6 over PRMT1 (IC 50 = 0.1 ± 0.025 µM) and PRMT8 (IC 50 = 0.11 ± 0.01 µM). MCE has not ind Biological Activity:MS117 is a first-in-class and cell-active irreversible protein arginine methyltransferase 6 (PRMT6) covalent inhibitor, with an IC 50 of 18 nM.

分子式

C17H22N4O

分子量

298.38 g/mol

Smiles

NCCN(C)CC1=CNC=C1C2=CC=CC(NC(C=C)=O)=C2

溶解性

DMSO : 100 mg/mL (335.14 mM; Need ultrasonic)

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

Warm reminder：

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！