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Product introduction
甲灭酸是一种氨基苯甲酸,是邻氨基苯甲酸,其中氮上连接的一个氢被2,3-二甲基苯基取代。虽然归类为非甾体抗炎药,但其抗炎特性被认为较小。它用于缓解轻度至中度疼痛,包括头痛、牙痛、骨关节炎和类风湿关节炎。它具有非甾体抗炎药、镇痛药、解热药、EC 1.14.99.1(前列腺素-内过氧化物合酶)抑制剂、外源性物质、抗风湿药和环境污染物的作用。它是一种氨基苯甲酸和仲胺化合物。
Chinese name
甲芬那酸, 环氧化酶抑制剂
English name
2-(2,3-dimethylanilino)benzoic acid
Chinese alias
扑湿痛 | 甲灭酸
English alias
Acidum mefenamicum | EINECS 200-513-1 | MLS000069709 | 2-[(2,3-dimethylphenyl)amino]benzoic acid | Mefenacid | MEFENAMIC ACID (USP-RS) | Benzoic acid, 2-(2,3-dimethylphenyl)amino- | NCGC00016278-07 | Prestwick2_000054 | 367589PJ2C | Anthranilic acid,3-xyl
CAS number
61-68-7
molecular formula
C15H15NO2
molecular weight
241.28
Exact mass
-
PSA
49.3
Logp
5.1
Safety
  • Regulatory information: 新西兰化学品状态清单: 甲灭酸: 无单独批准但可在适当的团体标准下使用
  • interaction: 口服抗凝剂的作用增强。
  • Hepatotoxicity: 可能性评分: D(可能是临床上明显的肝损伤的罕见原因)。
  • Other safety information: 化学品评估: IMAP 评估 - 苯甲酸, 2-[(2,3-二甲基苯基)氨基]-: 人类健康第一级评估
  • Hazard categories and classifications: 特定靶器官毒性 - 重复暴露 - 1类 (肾脏, 消化系统, 血液)
  • Non-human toxic extract: 猫和大鼠的脑电图显示,甲灭酸在低剂量时产生中枢短暂抑制效应,在高剂量时产生促进或刺激效应。
  • Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2019.09.022
  • Effects During Pregnancy and Lactation: ◉ 对哺乳和母乳的影响
Related
upstream information
Manufacturing method:
O-氯苯甲酸(CID:8374); 2,3-二甲基苯胺(CID:6893); 碳酸钾(CID:11430)
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Research chemical CAS 61-68-7 10mM 1ml

Research chemical CAS 61-68-7 10mM 1ml, complete specifications, for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:M795712-1ml
Product model:1ml
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Lead Time:30days
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