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Product introduction
米力农是联吡啶类化合物,是3,5,6位分别被氰基、吡啶-4-基和甲基取代的2-吡啶酮。它用于(特别是静脉注射,以乳酸盐形式)严重心力衰竭的短期治疗。它具有血管扩张剂、强心药、血小板聚集抑制剂和EC 3.1.4.17(3',5'-环核苷酸磷酸二酯酶)抑制剂的作用。它是腈类、吡啶酮和联吡啶类化合物。
Chinese name
米利酮, 磷酸二酯酶 2A 抑制剂
English name
6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile
Chinese alias
-
English alias
(3,4'-BIPYRIDINE)-5-CARBONITRILE, 1,6-DIHYDRO-2-METHYL-6-OXO- | 1,2-DIHYDRO-6-METHYL-2-OXO-5-(4-PYRIDINYL)NICOTINONITRILE | MILRINONE [VANDF] | Prestwick2_001065 | HMS3370H18 | Tox21_500737 | MILRINONE (MART.) | C01CE02 | Corotrope | HMS2090J14 | HMS2098E
CAS number
78415-72-2
molecular formula
C12H9N3O
molecular weight
211.22
Exact mass
-
PSA
65.8
Logp
0.000
Safety
  • Harmful effect: 除了其血流动力学和致心律失常作用外,米力农还可能影响血小板功能和炎症途径。它可能抑制血小板聚集,抑制与内皮损伤相关的内膜增生,并减轻心肺旁路的促炎作用。
  • Toxicity summary: 重要的是,米力农没有解毒剂。因此,在过量情况下,应停止使用米力农,直到患者病情稳定。临床医生应针对过量症状进行治疗,重点关注血流动力学参数和心律失常。
  • Hazard categories and classifications: 急性毒性 3 (93.2%)
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98% 250/mg

98% 250/mg Macklin 78415-72-2, available in complete specifications for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials

item number:M830571-250mg
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