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Product introduction
根据州或联邦政府标签要求,尼莫地平可导致发育毒性。
Chinese name
尼莫地平, Ca v1.1的门控抑制剂
English name
3-O-(2-methoxyethyl) 5-O-propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Chinese alias
-
English alias
Nimodipine ap | SPECTRUM1503600 | 2-methoxyethyl propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate | 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-methoxyethyl 1-methylethyl ester | DTXCID0033
CAS number
66085-59-4
molecular formula
C21H26N2O7
molecular weight
418.4
Exact mass
-
PSA
120
Logp
3.1
Safety
  • Harmful effect: 包括卡马西平、苯巴比妥(苯巴比妥钠)和苯妥英在内的药物是CYP3A4诱导剂。同时使用这些任何一种药物都会增强尼莫地平的代谢。这个过程会降低尼莫地平的血清浓度,增加治疗失败的可能性。
  • Toxicity summary: 没有特定的解毒剂。过量时首先应停止使用尼莫地平并治疗症状。如果毒性是由于口服摄入引起的,可以考虑洗胃,紧急情况下可以给予活性炭。低血压用正性肌力药治疗,心律失常由心脏病专家和急诊科人员管理。由于尼莫地平与蛋白质高度结合,透析可能没有效果。最近的病例报告表明,羟钴胺可能是尼莫地平引起的顽固性血管麻痹的潜在救援疗法。
  • Regulatory information: 加州化妆品安全计划(CSCP)报告成分:报告 - 无论成分在产品中的预期功能如何
  • Hazard categories and classifications: 特定靶器官毒性-重复接触 2 (58.2%)
  • Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2019.09.022
  • Effects During Pregnancy and Lactation: ◉ 对哺乳和母乳的影响
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Research chemical 1g; ≥98%

Research chemical 1g; ≥98%; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 1g; ≥98%.

item number:N129506-1g
Product model:1g
level: 1g; ≥98%
Lead Time:30days
sold 43 Items
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Specifications:

1g

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