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Product introduction

N3-PEG3-VC-PAB-MMAF（Comp T-88-5）是一种药物连接物偶联物，含有 ADC 连接物 N3-PEG3-VC-PAB 和微管蛋白抑制剂 MMAF。N3-PEG3-VC-PAB-MMAF 是一种点击化学试剂。它含有 Azide 基团，可以和含有 Alkyne 基团的分子发生铜催化的叠氮-炔环加成反应（CuAAc)。它还可以和含有 DBCO 或 BCN 基团的分子发生环张力驱动的炔-叠氮环加成反应 (SPAAC)。 N3-PEG3-VC-PAB-MMAF (Comp T-88-5) is a drug-linker conjugate containing the ADC linker N3-PEG3-VC-PAB and the tubulin inhibitor MMAF[1]. N3-PEG3-VC-PAB-MMAF is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Specs ⸢ View details ⸥

Chinese name

N3-PEG3-VC-PAB-MMAF

English name

N3-PEG3-VC-PAB-MMAF

Chinese alias

English alias

CAS number

2757277-32-8

molecular formula

C66H105N13O17

molecular weight

1352.62 g/mol

Exact mass

PSA

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