Share to

Details

Safety

Technical Documents

Articles

reviews

Consult

returns

Product details

名称

187-1, N-WASP 抑制剂 TFA

货号

N287721-10mg

包装规格

10mg

浓度

≥98%

产品介绍

187-1, N-WASP inhibitor TFA 是一种14-aa 环肽，也是一种变构神经 Wiskott Aldrich 综合征蛋白 (N-WASP) 抑制剂。187-1, N-WASP inhibitor TFA 有效抑制由磷脂酰肌醇 4,5-二磷酸酯 (PIP2) 诱导的肌动蛋白装配，IC50 为 2 μM。187-1, N-WASP inhibitor TFA 通过稳定蛋白质的自抑制状态，阻止了 N-WASP 激活 Arp2/3。 187-1, N-WASP inhibitor TFA, a 14-aa cyclic peptide, is an allosteric neural Wiskott-Aldrich syndrome protein (N-WASP) inhibitor. 187-1, N-WASP inhibitor TFA potently inhibits actin assembly induced by phosphatidylinositol 4,5-bisphosphate (PIP2) with an IC50 of 2 μM. 187-1, N-WASP inhibitor TFA prevents the activation of Arp2/3 complex by N-WASP by stabilizing the autoinhibited state of the protein.

生化机理

通过稳定蛋白质的自动抑制状态来抑制神经Wiskott-Aldrich综合征蛋白质（N-WASP）。阻断磷脂酰肌醇4,5-二磷酸（PIP2）刺激的肌动蛋白组装（IC50〜2μM），但不直接抑制肌动蛋白聚合。

序列

KFPFFPQ KFPFFPQ(Modifications: Phe-2 = D-Phe, Pro-3 = D-Pro, Phe-4 = D-Phe, Pro-6 = D-Pro, Cyclized)

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

Warm reminder：

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！