- Harmful effect： * 尼索地平可能与大蒜和姜黄相互作用。尼索地平作用于UGT (UDP-葡糖醛酸转移酶)。大蒜和姜黄抑制UGT，这会增加尼索地平的血清浓度。避免同时使用。
- Toxicity summary： 如果怀疑中毒，复苏是首要任务。需要静脉输液和阿托品治疗心动过缓，同时临床人员需频繁评估。如果患者出现严重症状，保持气道通畅、静脉输注等渗晶体液、钙盐、胰高血糖素、胰岛素和血管加压药治疗都是可行的选择。所有疑似尼索地平过量的患者都应给予活性炭。由于血浆蛋白结合率高，透析对尼索地平过量通常无效。体外生命支持与严重钙通道阻滞剂中毒相关心脏骤停患者的生存率提高相关。
- Hazard categories and classifications： 水环境慢性2类 (34.8%)
- Drug Induced Liver Injury： 参考文献：DOI:10.1016/j.drudis.2019.09.022
- Effects During Pregnancy and Lactation： ◉ 对哺乳和母乳的影响
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Research chemical 1ml
Research chemical 1ml; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 1ml.
