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名称
柚皮苷二氢查尔酮
英文别名
Glucopyranoside, 3,5-dihydroxy-4-(p-hydroxyhydrocinnamoyl)phenyl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-, beta-D- | s2389 | naringin dihydrochalcone, AldrichCPR | AS-12149 | 1-(4-(((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-
英文名称
Naringin dihydrochalcone
货号
N422317-1ml
包装规格
1ml
浓度
10mM in DMSO
储存温度
-80℃储存
运输条件
超低温冰袋运输
产品介绍
A citrus bioflavonoid that is also an inhibitor of CYP enzymes. A citrus bioflavonoid that is also an inhibitor of CYP enzymes.
生化机理
柚皮苷二氢查尔酮是一种柑橘类生物黄酮,可抑制小鼠肝脏中细胞色素 P450 单氧化酶的活性。柚皮苷二氢查尔酮可防止毒素引起的细胞骨架破坏和肝细胞凋亡。此外,研究还发现它通过抑制 HMG-CoA 还原酶和 ACAT 活性,具有降低胆固醇的作用。
CAS号
18916-17-1
分子式
C27H34O14
分子量
582.55 g/mol
PubChem编号
9894584
Isomeric SMILES
C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2OC3=CC(=C(C(=C3)O)C(=O)CCC4=CC=C(C=C4)O)O)CO)O)O)O)O)O
IIUPAC Name
1-[4-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-2,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)propan-1-one
INCHI
1S/C27H34O14/c1-11-20(33)22(35)24(37)26(38-11)41-25-23(36)21(34)18(10-28)40-27(25)39-14-8-16(31)19(17(32)9-14)15(30)7-4-12-2-5-13(29)6-3-12/h2-3,5-6,8-9,11,18,20-29,31-37H,4,7,10H2,1H3/t11-,18+,20-,21+,22+,23-,24+,25+,26-,27+/m0/s1
InChi Key
CWBZAESOUBENAP-QVNVHUMTSA-N
Smiles
CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=CC(=C(C(=C3)O)C(=O)CCC4=CC=C(C=C4)O)O)CO)O)O)O)O)O
氢键供体数Hydrogen Bond Donor Count
9
氢键受体数Hydrogen Bond Acceptor Count
14
可旋转键计数Rotatable Bond Count
9
精确质量Exact Mass
582.195 Da
单同位素质量Monoisotopic Mass
582.195 Da
拓扑极表面积Topological Polar Surface Area
236.000 Ų
重原子数Heavy Atom Count
41
形式电荷Formal Charge
0
复杂度Complexity
827.000
同位素原子数Isotope Atom Count
0
共价键合单元计数Covalently-Bonded Unit Count
1
XLogP3
-0.300
Reaxy-Rn
39917672
Safety
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Research chemical 1ml

Research chemical 1ml; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 1ml.

item number:N422317-1ml
Product model:1ml
level: 1ml
Lead Time:30days
sold 380 Items
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