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Product introduction
一种低毒性的组胺H2受体拮抗剂,可抑制胃酸分泌。该药物用于治疗十二指肠溃疡。
Chinese name
尼扎替丁
English name
1-N'-[2-[[2-[(dimethylamino)methyl]-1,3-thiazol-4-yl]methylsulfanyl]ethyl]-1-N-methyl-2-nitroethene-1,1-diamine
Chinese alias
尼扎替丁
English alias
HMS2051K04 | Nizax | Axid (TN) | DTXCID403376 | NCGC00016934-06 | NSC759289 | AC-5272 | MLS000759518 | Niaztidine | (E)-N-{2-[({2-[(dimethylamino)methyl]-1,3-thiazol-4-yl}methyl)thio]ethyl}-N'-methyl-2-nitroethene-1,1-diamine | N-(2-(((2-((Dimethylamino)m
CAS number
76963-41-2
molecular formula
C12H21N5O2S2
molecular weight
331.5
Exact mass
-
PSA
140
Logp
1.6
Safety
  • Disposal method: SRP:在审查时,土地处理或填埋(卫生填埋)处置实践的标准正在重大修订中。在实施废物残渣(包括废物污泥)的土地处置之前,咨询环境监管机构以获取可接受的处置实践指导。
  • interaction: 当尼扎替丁与茶碱、利多卡因、华法林、氯氮卓、地西泮或劳拉西泮同时使用时,未报告有药物相互作用。
  • Hepatotoxicity: 可能性评分: D(可能是临床上明显的肝损伤的罕见原因)。
  • Human toxicity extract: 尼扎替丁可能抑制胃粘膜中的乙醇脱氢酶,导致血清酒精水平升高,但这似乎没有临床意义。
  • Other safety information: 化学品评估:IMAP评估 - 1,1-乙烯二胺,N-[2-[[[2-[(二甲基氨基)甲基]-4-噻唑基]甲基]硫基]乙基]-N'-甲基-2-硝基-:人类健康I级评估
  • Hazard categories and classifications: 急性毒性 4 (97.6%)
  • Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2019.09.022
  • Effects During Pregnancy and Lactation: 已知组胺H2受体阻断会刺激催乳素分泌。截至修订日期,未发现尼扎替丁引起高催乳素血症、溢乳或对哺乳妇女影响的报告。已建立哺乳的母亲体内的催乳素水平可能不会影响她母乳喂养的能力。
  • USGS Health-Based Screening Levels for Evaluating Water-Quality: 参考文献: Smith, C.D. and Nowell, L.H., 2024. 用于评估水质数据的基于健康的标准水平 (第 3 版)。DOI:10.5066/F71C1TWP
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butyl 1ml

H 2 reagent

item number:N425893-1ml
Product model:1ml
level:
Lead Time:30days
sold 439 Items
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Specifications:

1ml

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