- Harmful effect： * 氨基糖苷类：氨基糖苷类抗生素，如链霉素、新霉素和卡那霉素，具有非去极化神经肌肉阻滞作用。同时给药需要调整剂量并谨慎。
- Toxicity summary： 如果新斯的明过量/中毒，应立即给予阿托品。通过监测肌肉抽搐反应可以最小化过量风险。如果发生过量，必要时提供人工通气并监测心脏功能。在肌无力危象中，管理涉及增加抗胆碱酯酶药物的剂量以改善肌肉力量。可以给予阿托品以对抗毒蕈碱样不良反应，如由较高剂量抗胆碱酯酶药物引起的心动过缓。在胆碱能危象中，应立即停止所有抗胆碱酯酶药物，并给予阿托品以对抗过量乙酰胆碱的毒蕈碱样作用。如果呼吸功能...
- Human toxicity extract： ...对中枢神经系统的影响包括意识混乱、共济失调、言语不清、反射丧失、潮式呼吸、全身性惊厥、昏迷和中央呼吸麻痹。...单次急性暴露后的死亡时间可能从不到5分钟到近24小时不等，取决于剂量、途径、药物...死亡原因主要是呼吸衰竭，通常伴有继发性心血管成分。/抗胆碱酯酶剂/
- Non-human toxic extract： 形态学技术被用于测定新斯的明对大鼠肌肉的急性和慢性影响。短暂性钙沉积与纤维类型无关，并出现在与新斯明诱导的局灶性病变相对应的部位。特征性中间发现包括杆状体和核糖体簇。这些簇经常与混合和聚集的肌浆网、T系统或线粒体混合。局灶性肌病变化是可逆的，除了神经肌肉接头区域的病变。
- Effects During Pregnancy and Lactation： 一项研究比较了新斯的明和瑞加德克斯在剖宫产手术全身麻醉下对哺乳相关激素的影响。两组术后孕酮和雌二醇水平与术前相比均显著下降；然而，瑞加德克斯组下降幅度更大。醛固酮水平在手术结束时达到最高点，但4小时后低于手术前水平，瑞加德克斯组尤其如此。皮质醇显示术后暂时性升高，而催乳素和催产素水平在两组中均上升，组间无显著差异。
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neostigmine 5mg
neostigmine 5mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 5mg.
