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Product introduction

NPD1335 is a Trypanosoma brucei phosphodiesterase B1 ( TbrPDEB1 ) inhibitor with submicromolar activities against T. brucei parasites. NPD1335 displays a greatly improved cytotoxicity profile. NPD1335 increases intracellular cAMP levels and results in the distortion of the cell cycle and cell death Form:Solid IC50& Target:pKi: 6.9 (TbrPDEB1),pIC50: 6.2 (T. brucei) (NPD-1335)

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Chinese name

NPD-1335

English name

NPD-1335

Chinese alias

English alias

CAS number

2376326-31-5

molecular formula

C28H29N3O3

molecular weight

455.55 g/mol

Exact mass

≥98%

PSA

Logp

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