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名称

Nav1.7-IN-2

英文名称

Nav1.7-IN-2

货号

N655244-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

-80℃储存

运输条件

超低温冰袋运输

产品介绍

Nav1.7-IN-2 is an inhibitor of voltage-gated sodium channels (Nav), in particular Nav 1.7, with IC50 of 80 nM.IC50 value: 80 nMTarget: Nav 1.7Nav1.7-IN-2 is useful for the treatment of diseases treatable by inhibition of these channels, in particular, chronic pain disorder. The more detailed information please refer to WO 2011103196 A1. Nav1.7-IN-2 is a Nav1.7 channel inhibitor extracted from patent WO/2011103196 A1, compound example J, has an IC50 of 80 nM. IC50& Target:Na v 1.7 80 nM (IC 50 )

生化机理

Nav1.7-IN-2 是电压门控钠通道（Nav），特别是 Nav 1.7 的抑制剂，IC50 值为 80 nM：Nav1.7-IN-2可用于治疗通过抑制这些通道（尤其是 Nav 1.7）而可治疗的疾病。

CAS号

1332295-35-8(DMSO)

分子式

C22H22FN5O2

分子量

407.44 g/mol

Smiles

C(NC)(=O)C1=CC=CC(NC2=NC=CC(N3CC(OC4=CC=C(F)C=C4C)C3)=N2)=C1

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

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