Share to

Details

Safety

Technical Documents

Articles

reviews

Consult

returns

Product details

名称

NG-497

英文名称

NG-497

货号

N656080-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

避光,干燥,-80℃储存

运输条件

超低温冰袋运输

产品介绍

NG-497 is a selective human adipose triglyceride lipase ( ATGL ) inhibitor that targets the enzymatically active patatin-like domain of human ATGL. NG-497 has potential value for tumor research. In Vitro NG-497 selectively inactivates human and nonhuman primate ATGL but not structurally and functionally related lipid hydrolases and abolishes human adipocytes in a dose-dependent and reversible manner Lipolysis. NG-497 (40 μM, 80 min) reduces lipolysis-dependent respiration in HepG2 cells without impairing mitochondrial function through off-target effects. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

生化机理

NG-497 是一种选择性人脂肪甘油三酯脂酶（ATGL）抑制剂，其靶标是具有酶活性的人 ATGL 蛋白样结构域。NG-497 具有潜在的肿瘤研究价值。

CAS号

2598242-66-9(DMSO)

分子式

C18H21NO4

分子量

315.36 g/mol

Smiles

O=C(C1=CC(OC)=CC(C2=CC=C(OCC)C=C2)=N1)OC(C)C

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

Warm reminder：

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！