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Product introduction
物理描述 | 曲吡那胺是有胺气味的油状液体。(NTP, 1992)
Chinese name
tripelennamine, H 1 受体拮抗剂
English name
N'-benzyl-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine
Chinese alias
曲吡那敏
English alias
SPBio_000954 | TRIPELENNAMINE [HSDB] | 2-(N-Benzyl-N-(2-dimethylaminoethyl)amino)pyridine | 3C5ORO99TY | 2-(Benzyl(2-dimethylaminoethyl)amino)pyridine | DivK1c_000534 | DTXCID803717 | N-Benzyl-N',N'-dimethyl-N-2-(pyridylethylene)diamine | Spectrum4_000374
CAS number
91-81-6
molecular formula
C16H21N3
molecular weight
255.36
Exact mass
-
PSA
19.4
Logp
3.3
Safety
  • Health hazard: 症状:接触该化合物的症状可能包括欣快感、再生障碍性贫血、兴奋、幻觉、共济失调、不协调、手足徐动、惊厥、癫痫后抑郁、口干、瞳孔固定放大、面部潮红、发热、中枢神经系统抑制、嗜睡和昏迷。(NTP, 1992)
  • reactive group: 胺类、膦类和吡啶类
  • Disposal method: SRP:在审查时,土地处理或填埋(卫生填埋)处置实践的标准正在重大修订中。在实施废物残渣(包括废物污泥)的土地处置之前,咨询环境监管机构以获取可接受的处置实践指导。
  • First aid measures: 食入:不要催吐。如果受害者意识清醒且没有抽搐,给予1-2杯水稀释化学物质,并立即呼叫医院或中毒控制中心。如果医生建议,准备将受害者送往医院。如果受害者抽搐或昏迷,不要经口给予任何东西,确保受害者的气道通畅,让受害者侧卧,头部低于身体。不要催吐。立即将受害者送往医院。(NTP, 1992)
  • Regulatory information: 新西兰 EPA 化学品状态清单:曲吡那胺:没有单独批准,但可作为受团体标准覆盖的产品中的成分使用。不允许以其自身形式作为化学品使用。
  • fire hazard: 该化学品的闪点数据不可用。它可能是可燃的。(NTP, 1992)
  • fire fighting: 涉及此材料的火灾可以用干化学灭火器、二氧化碳或哈龙灭火器控制。(NTP, 1992)
  • reactivity profile: 曲吡那胺与酸发生放热反应中和形成盐和水。可能与异氰酸酯、卤代有机物、过氧化物、酚类(酸性)、环氧乙烷、酸酐和酰卤不相容。与强还原剂(如氢化物)结合可能产生易燃的氢气。
  • Other safety information: 化学品评估:IMAP评估 - 1,2-乙二胺,N,N-二甲基-N'-(苯甲基)-N'-2-吡啶基-:环境I级评估
  • Air and water reaction: 水溶性。
  • Hazard categories and classifications: 水环境慢性2(100%)
  • Non-fire leakage response: 储存注意事项:您应将此材料存放在冰箱中。(NTP, 1992)
  • Personal protective equipment (PPE): 推荐呼吸器:在称量和稀释纯测试化学品时,佩戴NIOSH批准的半面罩呼吸器,配备有机蒸气/酸性气体 cartridges(专门用于有机蒸气、HCl、酸性气体和SO2)和粉尘/雾过滤器。(NTP,1992)
  • Antidote and first aid: 抗组胺药中毒无特异性疗法,治疗应遵循一般症状性和支持性原则。...如果呼吸衰竭,机械通气支持比使用容易引发或加重惊厥阶段的 analeptics 更安全、...有效。/抗组胺药/
  • Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2019.09.022
  • Effects During Pregnancy and Lactation: 注射给药的相对高剂量抗组胺药可降低非哺乳期妇女和产后早期妇女的基础血清催乳素。然而,产后母亲使用抗组胺药预处理不影响哺乳引起的催乳素分泌。较低口服剂量的抗组胺药是否对血清催乳素有相同影响,或催乳素的变化对母乳喂养成功有任何后果尚未研究。已建立哺乳期的母亲的催乳素水平可能不会影响她的母乳喂养能力。
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upstream information
Manufacturing method:
O-氨基吡啶(CID:10439);β-二甲氨基乙基氯化物(CID:7901);氨基钠(CID:24533);苄基溴(CID:7498);曲吡那敏(CID:5587);柠檬酸(CID:311);柠檬酸盐(CID:31348);吡啶(CID:1049);氯化氢(CID:313)
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Research chemical CAS 91-81-6 98% 1g

Macklin Research chemical CAS 91-81-6 98% 1g, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

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