神经氨酸酶 来源于霍乱弧菌

N755091-1unit

1unit

Type II, buffered aqueous solution, 8-24 units/mg protein (Lowry, using NAN-lactose)

来自霍乱弧菌的神经氨酸酶已被用于一项描述五步纯化方法的研究中。 它还被用于一项探究白血病L1210肿瘤细胞修饰的研究中。 神经氨酸酶被用作糖缀合物分布和底物特异性研究的细胞表面探针。应用： 神经氨酸酶是一种促进流感病毒从感染细胞释放并促进病毒传播的水解酶。 量热法研究表明，神经氨酸酶中心催化结构域侧翼的两个凝集素样结构域可作为含唾液酸底物的识别和结合位点。 Calorimetry studies show that the two lectin-like domains flanking the central catalytic domain of Neuraminidase serve as the recognition and binding sites for sialic acid-containing substrates. Neuraminidase enzymes are hydrolase enzymes that promote influenza virus release from infected cells and facilitate virus spread. Application: Neuraminidase from Vibrio cholera has been used in a study to describe a five-step purification method. It has also been used in a study to investigate modification of leukemia L1210 tumor cells. Neurminidase is used as a cell-surface probe for glycoconjugate distribution and in substrate specificity studies.