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Product introduction
BKM120 (NVP-BKM120, Buparlisib)是一种选择性PI3K抑制,作用于p110α/β/δ/γ时,IC50分别为52 nM/166 nM/116 nM/262 nM,对VPS34, mTOR, DNAPK作用效果降低,对PI4Kβ几乎没有抑制活性。Phase 2。 A PI 3-kinase family inhibitor BKM120 is a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM, respectively. Reduced potency against VPS34, mTOR, DNAPK, with little activity to PI4Kβ. Phase 2. A PI 3-kinase family inhibitor
Chinese name
BKM120,体外PI3K抑制剂, PI3 激酶 I 类抑制剂
English name
BKM120
Chinese alias
-
English alias
AC-35575 | CHEBI:71954 | GTPL7878 | BUPARLISIB [WHO-DD] | AM85983 | HMS3295I15 | SCHEMBL823947 | BKM120,NVP-BKM120 | 3qdd | 5-[2,6-Di(Morpholin-4-Yl)pyrimidin-4-Yl]-4-(Trifluoromethyl)pyridin-2-Amine | BKM 120 | Buparlisib [INN] | 5-(2,6-di-4-morpholinyl-
CAS number
944396-07-0
molecular formula
C18H21F3N6O2
molecular weight
410.4 g/mol
Exact mass
-
PSA
89.600 Ų
Logp
1.5
Technical Documents
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NVP-BKM120, Buparlisib, BKM120 10mM in DMSO 1ml

NVP-BKM120, Buparlisib, BKM120 10mM in DMSO 1ml Macklin 944396-07-0, complete specifications, for production, research, laboratory testing and inspection, digital one-stop procurement platform for scientific materials.

item number:N798066-1ml
Product model:1ml
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Lead Time:30days
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