Nitronium tetrafluoroborate has been shown to be a versatile nitrating agent for nitrogen compounds, giving the corresponding N-nitro derivative when reacted with secondary aliphatic amines, an acyl aliphatic amine, a carbamate ester: a diacyl amine and primary amides. Application Usually used as reactant for preparation of nitro-derivatives of chlorambucil conjμgated to prasterone and pregnenolone as anticancer agents,nano-sized cryptomelane particles for the formation of potentiometric potassium ion sensors,Nitro- and aminoindole derivatives.And also used as oxidizing agent in high-power Li-ion battery technology for large-scale applications as required for plμg-in hybrid vehicles.