储存在-20℃。存放在干燥的条件下。该产品最多可存储12个月。 NSC 663284 (DA-3003-1) 是一种有效的，细胞可渗透的且不可逆的 Cdc25 dual specificity phosphatase 抑制剂，Cdc25B2 的 IC50 为 0.21 μM。NSC 663284 表现出与 Cdc25A，Cdc25B2 和 Cdc25C 的混合竞争动力学，Ki 值分别为 29、95 和 89 nM。NSC 663284 通过与 SET 结构域 (Kd of 370 nM) 的相互作用来抑制 NSD2 (IC50 of 170 nM) 酶的活性。 Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. product description： NSC 663284 (DA-3003-1) is a potent, cell-permeable, and irreversible Cdc25 dual specificity phosphatase inhibitor, has an IC50 for Cdc25B2 of 0.21 μM. NSC 663284 exhibits mixed competitive kinetics against Cdc25A, Cdc25B(2), and Cdc25C with Ki values of 29, 95, and 89 nM, respectively. NSC 663284 inhibits NSD2 (IC50 of 170 nM) through a direct interaction with the catalytic SET domain (Kd of 370 nM) application： NSC 663284 has been used as a cell division cycle 25 (CDC25) inhibitor to study its effects on the level of kizuna (kiz) dephosphorylation. It has also been used as a control in horseradish peroxidase/phenol red based assay and resazurin-based redox assay.