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Product introduction

Information PF-00835231 PF-00835231 is a 3CL pro (M pro ) inhibitor that may targets SARS-CoV-2 protease 3CL pro as a potential new treatment for COVID-19. Targets 3CL pro In vitro A time-of-drug-addition approach delineates the timing of early SARS-CoV-2 life cycle steps in A549 +ACE2 cells and validates PF-00835231\'s early time of action. In a model of the human polarized airway epithelium, PF-00835231 potently inhibits SARS-CoV-2 at low micromolar concentrations. PF-00835231 exhibits the potential as an effective SARS-CoV-2 antiviral. Cell Research(from reference) Cell lines：A549 cells, human airway epithelial cultures (HAEC) Concentrations：1 nM-10 μM Incubation Time：0-4 h

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Chinese name

PF-00835231

English name

PF-00835231

Chinese alias

English alias

(S)-3-((S)-2-(4-Methoxy-1H-indole-2-carboxamido)-4-methylpentanamido)-2-oxo-4-((S)-2-oxopyrrolidin-3-yl)butanol | compound 4 [Hoffman et al., 2020] | PF00835231 | PF-00835231 | N-[(2S)-1-[[(2S)-4-hydroxy-3-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl]amino

CAS number

870153-29-0

molecular formula

C24H32N4O6

molecular weight

472.53 g/mol

Exact mass

PSA

150.000 Å²

Logp

1.107

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Research chemical CAS 870153-29-0 95% 5mg

Name: Research chemical CAS 870153-29-0 95% 5mg
Brand: 麦克林
SKU: N975263-5mg

Research chemical CAS 870153-29-0 95% 5mg, complete specifications, for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：N975263-5mg

Product model：5mg

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Research chemical CAS 870153-29-0 95% 5mg

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