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Product introduction

OSU-03012 (AR-12)是一种有效的重组PDK-1抑制剂，IC50为5 μM，比OSU-02067作用效果高2倍。A PDK1 inhibitor and inducer of caspase and p53-independent apoptosis. OSU-03012 is a potent inhibitor of recombinant PDK-1 with IC50 of 5 μM and 2-fold increase in potency over OSU-02067. A PDK1 inhibitor and inducer of caspase and p53-independent apoptosis.

Specs ⸢ View details ⸥

Chinese name

OSU-03012 (AR-12),PDPK1（PDK1）抑制剂, 3-磷酸肌酸依赖性蛋白激酶-1 抑制剂

English name

OSU-03012 (AR-12)

Chinese alias

English alias

PDK1 inhibitor AR-12 | 9-Fluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate | DTXSID50225206 | AS-19550 | OSU-03012 | FT-0721533 | N-(4-(5-(2-Phenanthryl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)ethane-1,2-diamine | SCHEMBL570472 | AR

CAS number

742112-33-0

molecular formula

C26H19F3N4O

molecular weight

460.46 g/mol

Exact mass

PSA

72.900 Å²

Logp

5.2

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