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Product introduction

Information Ombitasvir (ABT-267) Ombitasvir (ABT-267) is an inhibitor of the HCV non-structural protein 5A with antiviral activity. Targets NS5A In vitro Ombitasvir (ABT-267) is a hepatitis C virus (HCV) NS5A inhibitor with picomolar potency, pan-genotypic activity, and 50% effective concentrations (EC50s) of 0.82 to 19.3 pM against HCV genotypes 1 to 5 and 366 pM against genotype 6a. Ombitasvir has EC50s of 14.1 and 5.0 pM against genotype 1a-H77 and 1b-Con1 subgenomic replicons, respectively.

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Chinese name

奥比他韦(ABT-267), 非结构蛋白 5A 抑制剂

English name

Ombitasvir (ABT-267)

Chinese alias

English alias

Methyl ((S)-1-((S)-2-((4-((2S,5S)-1-(4-(tert-butyl)phenyl)-5-(4-((S)-1-((methoxycarbonyl)-L-valyl)pyrrolidine-2-carboxamido)phenyl)pyrrolidin-2-yl)phenyl)carbamoyl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)carbamate | BDBM50453112 | C72037 | EN300-2035213

CAS number

1258226-87-7

molecular formula

C50H67N7O8

molecular weight

894.11 g/mol

Exact mass

PSA

179.000 Å²

Logp

7.103

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