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Product introduction

Information 6-OAU 6-OAU (GTPL5846, 6-n-octylaminouracil) is a surrogate agonist of G protein-coupled receptor 84 (GPR84) that activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with EC50 of 105 nM in the PI assay. 6-OAU (GTPL5846, 6-n-octylaminouracil) increases [35S]GTPγS incorporated in Sf9 cell membranes expressing human GPR84-Gαi fusion protein with EC50 of 512 nM. Targets hGPR84 (in the PI assay); human GPR84-Gαi fusion protein (Cell-free assay) 105 nM(EC50); 512 nM(EC50)

Specs ⸢ View details ⸥

Chinese name

6-OAU, GPR84 的激动剂

English name

6-OAU

Chinese alias

English alias

GTPL5846 | 6-n-octylaminouracil

CAS number

83797-69-7

molecular formula

C12H21N3O2

molecular weight

239.31 g/mol

Exact mass

PSA

70.200 Å²

Logp

2.354

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