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Product introduction

ODN 24987 is a Guanine-modified inhibitory oligonucleotides (ODN), targeting TLR9 . ODN 24987 can inhibit IL-6 and IFN-α release. ODN 24987 can be used for research immune disorders. ODN 24987 sequence: 5’-C-C-T-G-G-C-c7G-G-G-G-3’ In Vitro ODN 24987 (0.1, 1 and 10 μM, 24 h) impairs efficiently TLR9-mediated release of IFN-α by PBMCs, and prevents IL-6 release by CpG-ODN-activated human B-cells. ODN 24987 (0.01, 0.1, 1, 10 μM; 48 h) impairs Imiquimod-induced IL-6 release by human PBMCs. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:TLR9

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Chinese name

ODN 24987

English name

ODN 24987

Chinese alias

域名 24987

English alias

CAS number

1682661-48-8

molecular formula

molecular weight

3229.60 g/mol

Exact mass

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