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Product introduction

Okanin, effective constituent of the flower tea Coreopsis tinctoria , attenuates LPS-induced microglial activation through inhibition of the TLR4 / NF-κB signaling pathways In Vitro Okanin significantly inhibits LPS-induced TLR4 expression in BV-2 cells. Okanin inhibits the translocation of the NF-κB p65 subunit from the cytosol to the nucleus. Okanin significantly suppresses LPS-induced iNOS expression and also inhibites IL-6 and TNF-α production and mRNA expression in LPS-stimulated BV-2 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:TLR4 p65

Specs ⸢ View details ⸥

Chinese name

Okanin

English name

Okanin

Chinese alias

奥卡宁

English alias

CAS number

484-76-4

molecular formula

C15H12O6

molecular weight

288.25 g/mol

Exact mass

≥98%

PSA

118.000 Å²

Logp

2.500

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