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名称

Orexin 2 Receptor Agonist

别名

食欲素 2 受体激动剂

英文名称

Orexin 2 Receptor Agonist

货号

O655404-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

-80℃储存

运输条件

超低温冰袋运输

产品介绍

Orexin 2 Receptor Agonist is a potent (EC50 on OX2R is 23 nM) and OX2R-selective (OX1R/OX2R EC50 ratio is 70) agonist.IC50 value: 23 nM (EC50)Target: Orexin 2 ReceptorOrexin 2 Receptor Agonist shows not only potentactivity but also high selectivity for OX2R over OX1R. In CHO cells overexpressing hOX1R and HEK-293 cells overexpressing hOX2R, compound 26 displaced [125I]orexin-A in a concentration dependent manner: 26 bound to hOX2R and hOX1R with Ki of 0.14 and 0.77 μM, respectively.

生化机理

Orexin 2 受体激动剂是一种强效（对 OX2R 的 EC50 值为 23 nM）且具有 OX2R 选择性（OX1R/OX2R EC50 比值为 70）的激动剂：催产素 2 受体激动剂不仅具有强大的活性，而且还具有高选择性。

CAS号

1796565-52-0(DMSO)

分子式

C32H34N4O5S

分子量

586.7 g/mol

Smiles

CC1=CC(=CC=C1)C(=O)NCCNC2=CC(=CC=C2)NS(=O)(=O)C3=C(C=CC(=C3)C4=CC(=CC=C4)C(=O)N(C)C)OC

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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