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Product details

名称

OTS186935 hydrochloride

别名

OTS186935 盐酸盐

英文名称

OTS186935 hydrochloride

货号

O661587-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

干燥,-80℃储存

运输条件

超低温冰袋运输

产品介绍

OTS186935 hydrochloride is a potent protein methyltransferase SUV39H2 inhibitor with an IC 50 of 6.49 nM. OTS186935 hydrochloride shows significant inhibition of tumor growth in mouse xenograft models without any detectable toxicity. OTS193320 hydrochlori IC50& Target:IC50: 6.49 nM (SUV39H2) In Vitro:OTS186935 hydrochloride inhibits A549 cell growth with an IC 50 of 0.67 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo:OTS186935 hydrochloride (10mg/kg or 25mg/kg; intravenously; once daily for 14 days) exhibits growth suppressive effects in human cancer cell line derived xenograft models. MCE has not independently confirmed the accuracy of these methods. They are Biological Activity:OTS186935 hydrochloride is a potent protein methyltransferase SUV39H2 inhibitor with an IC 50 of 6.49 nM. OTS186935 hydrochloride shows significant inhibition of tumor growth in mouse xenograft models without any detectable toxicity. OTS193320 hydrochlori

分子式

C25H26ClN5O2.8/5HCl

分子量

522.31 g/mol

Smiles

COC1=C(Cl)C=C(C2=CN3C=CC(N4C[C@@H](NCC5=CC=NC=C5)CC4)=CC3=N2)C(OC)=C1.[H]Cl.[8/5]

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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