7-O-(Amino-PEG4)-paclitaxel

7-O-(Amino-PEG4)-paclitaxel

O767769-5mg

5mg

≥99.8%

-20°C储存

超低温冰袋运输

7-O-(Amino-PEG4)-paclitaxel 是一种 PEG 类、用于 ADC 的药物-接头偶联物，包含一个紫杉醇部分和一个氨基基团。氨基能够与羧酸、活化的 NHS 酯、羰基（酮、醛）等反应。7-O-(Amino-PEG4)-paclitaxel 可用于 ADC 的合成。 7-O - (Amino-PEG4) - paclitaxel is a PEG based drug linker conjugate used for ADC, comprising a paclitaxel moiety and an amino group. Amino groups can react with carboxylic acids, activated NHS esters, carbonyl groups (ketones, aldehydes), etc. 7-O - (Amino-PEG4) - paclitaxel can be used for the synthesis of ADCs. Powder -20°C 3 years；In solvent -80°C 6 months，-20°C 1 month In vitro research PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins

7-O-(Amino-PEG4)-paclitaxel is a PEG-class Drug-linker conjugates for ADC, containing a paclitaxel moiety and a amino group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. 7-O-(Amino-PEG4)-paclitaxel can be used in the synthesis of Antibody-Drug Conjugates (ADCs)

C58H72N2O19

1101.19 g/mol