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Product introduction

Oltipraz抑制HIF-1α激活, 这种作用具时间依赖性, 浓度≥10μM时完全废除HIF-1α诱导, Oltipraz抑制HIF-1α, IC50为10μM。Oltipraz 是一种有效的 Nrf2 激活剂，也是一种有效的II期解毒酶诱导剂，显著作用于谷胱甘肽-S-转移酶(GST). Oltipraz has an inhibitory effect on HIF-1α activation by insulin in a time-dependent manner, completely abrogating HIF-1α induction at ≥10 μM concentrations, the IC50 of Oltipraz for HIF-1α inhibition is 10 μM. Oltipraz is a potent Nrf2 activator and a potent inducer of Phase II detoxification enzymes, most notably glutathione-S-transferase (GST).

Specs ⸢ View details ⸥

Chinese name

奥替普拉

English name

Oltipraz

Chinese alias

吡噻硫酮 | 1,2-二硫杂环戊烷-3-硫酮 | 4-甲基-5-(2-吡嗪基)-1,2-二噻环戊二烯-3-硫酮 | 4-甲基-5-(吡嗪-2-基)-3H-1,2-二硫杂环戊二烯-3-硫酮 | 4-甲基-5-(2-吡嗪基)-3H-1,2-二硫杂环戊二烯-3-硫酮

English alias

BCP16064 | RP 35972;NSC 347901 | BRN 0978110 | DTXSID7021079 | NSC347901 | NSC-347901 | Q7088765 | 4-methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione | A13164 | NSC759840 | NSC-759840 | MFCD00868499 | SR-05000001517-1 | AB01275510_02 | C8H6N2S3 | SMR00155

CAS number

64224-21-1

molecular formula

C8H6N2S3

molecular weight

226.34 g/mol

Exact mass

≥98%

PSA

108.000 Å²

Logp

1.100

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Bi Sai thioketone 10mM in DMSO 1ml

Name: Bi Sai thioketone 10mM in DMSO 1ml
Brand: 麦克林
SKU: O795683-1ml

Bi Sai thioketone 10mM in DMSO 1ml Macklin 64224-21-1, complete specifications, for production, research, laboratory testing and inspection, digital one-stop procurement platform for scientific materials.

item number：O795683-1ml

Product model：1ml

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Bi Sai thioketone 10mM in DMSO 1ml

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