Share to

Details

Safety

Technical Documents

Articles

reviews

Consult

returns

Product details

名称

Pam2CSK4 TFA

货号

P288184-1mg

包装规格

1mg

级别

Moligand™

浓度

≥95%

产品介绍

Pam2CSK4 (TFA)，一种脂肽，是一种不依赖于 TLR6 的 TLR2 配体和激动剂。Pam2CSK4 (TFA) 促进血小板聚集，并以 TLR2/NF-κB/BTK 依赖性方式增加血小板对胶原蛋白包被表面的粘附。Pam2CSK4 (TFA) 还可激活小鼠巨噬细胞中的 iNOS 表达和 NO 产生。分子式：C65H126N10O12S.xC2HF3O2 分子量：1271.82 (free base) CAS: 868247-72-7(free base) Pam2CSK4 (TFA), a lipopeptide, is a TLR6-independent TLR2 ligand and agonist. Pam2CSK4 (TFA) promotes platelet aggregation, and increases platelet adhesion to collagen-coated surfaces in a TLR2/NF-κB/BTK-dependent manner. Pam2CSK4 (TFA) also activates iNOS expression and NO production in mouse macrophages .

生化机理

Toll样受体2/6（TLR2 / 6）激动剂。在人单核细胞中诱导TNF-α的产生。还诱导小鼠脾脏B细胞的增殖和活化。

序列

CSKKKK(Modifications: Cys =S-[2,3-Bis(palmitoyloxy)-(2-R)-propyl]-Cys)

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

Warm reminder：

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！