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Product introduction

Phenamil是一种阿米洛利类似物。不可逆转地阻断ENaC（阿米洛利敏感的Na | + |通道）。 Phenamil is an amiloride analog. Irreversibly blocks ENaC (amiloride-sensitive Na|+|channels).Phenamil is a compound that promotes bone repair and regulates stem cell differentiation. It can activate the bone morphogenetic protein signaling pathway to promote bone repair, but it also induces adipogenesis. A specific 3D scaffold strategy can improve its induced osteogenic differentiation and reduce adipogenesis.

Specs ⸢ View details ⸥

Chinese name

Phenamil Hydrate, TRPP2 的通道阻断剂

English name

Phenamil Hydrate

Chinese alias

苯海拉明

English alias

Bio1_001134 | NCGC00162311-03 | Bio1_000645 | HMS3402H15 | MLS002172443 | Bio2_000153 | CID 5353878 | NCGC00162311-06 | SMR003929926 | Bio1_000156 | 3,5-diamino-N-[(1E)-amino(phenylamino)methylidene]-6-chloropyrazine-2-carboxamide | CBiol_001870 | BDBM115

CAS number

2038-35-9

molecular formula

C12H12ClN7O.xH2O

molecular weight

305.72 (anhy) g/mol

Exact mass

PSA

145.000 Å²

Logp

1.800

Technical Documents

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