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Product introduction

PEPA是AMPA脱敏的变构增强剂。PEPA降低了脱敏反应的发生率，并增强了Glu诱导的稳态平衡电流，并具有剪接变体和亚基选择性。PEPA增强了静脉给药后大鼠的缺血性记忆障碍。AMPA是由GluR-1、2、3、4亚基组成的跨膜谷氨酸受体。PEPA是GluR的激活剂。 PEPA is an allosteric potentiator of AMPA desensitization. PEPA decreases the rate of onset of desensitization and potentiates steady-state equilibrium currents induced by Glu with splic variant and subunit selectivity. PEPA enhances post-ischemic memory impairment in rats post i.v. administration. AMPA is a transmembrane glutamate receptor composed of the subunits GluR-1,2,3,4. PEPA is an activator of GluR.

Specs ⸢ View details ⸥

Chinese name

PEPA

English name

PEPA

Chinese alias

English alias

CAS number

141286-78-4

molecular formula

C16H16F2N2O4S2

molecular weight

402.44 g/mol

Exact mass

≥98%

PSA

132.000 Å²

Logp

2.2

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