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Product introduction
物理描述 | 晶体或白色粉末。(NTP, 1992)
Chinese name
-
English name
6-chloro-2-methyl-1,1-dioxo-3-(2,2,2-trifluoroethylsulfanylmethyl)-3,4-dihydro-1lambda6,2,4-benzothiadiazine-7-sulfonamide
Chinese alias
-
English alias
-
CAS number
346-18-9
molecular formula
C11H13ClF3N3O4S3
molecular weight
439.9
Exact mass
-
PSA
152
Logp
2.6
Safety
  • Health hazard: 急性/慢性危害:加热分解时,该化合物会释放剧毒烟雾。(NTP, 1992)
  • Storage conditions: ...应储存在避光容器中...
  • reactive group: 芳基卤化物
  • Disposal method: SRP:在审查时,土地处理或填埋(卫生填埋)处置实践的标准正在重大修订中。在实施废物残渣(包括废物污泥)的土地处置之前,咨询环境监管机构以获取可接受的处置实践指导。
  • First aid measures: 食入:不要催吐。如果受害者意识清醒且没有抽搐,给予1-2杯水稀释化学物质,并立即呼叫医院或中毒控制中心。如果医生建议,准备将受害者送往医院。如果受害者抽搐或昏迷,不要经口给予任何东西,确保受害者的气道通畅,让受害者侧卧,头部低于身体。不要催吐。立即将受害者送往医院。(NTP, 1992)
  • Regulatory information: 新西兰EPA化学品清单状态:2H-1,2,4-苯并噻二嗪-7-磺酰胺,6-氯-3,4-二氢-2-甲基-3-(2,2,2-三氟乙基)硫代甲基-, 1,1-二氧化物:没有单独批准但可在适当的团体标准下使用
  • fire hazard: 该材料的闪点数据不可用,但可能是可燃的。(NTP, 1992)
  • fire fighting: 涉及此材料的火灾可使用二氧化碳、干化学或哈龙灭火器控制。(NTP, 1992)
  • reactivity profile: 聚噻嗪是一种磺酰胺衍生物。与强还原剂反应会产生硫化氢气体。
  • Human toxicity extract: 可能抑制泌乳,但与母乳喂养兼容/SRP:/。/噻嗪类利尿剂,来自表格/
  • Air and water reaction: 其在溶液中的分解速率随pH值的增加而增加。(NTP, 1992)。不溶于水。
  • non-human toxicity value: LD50 狗口服 450 mg/kg
  • Milk Concentrations: 噻嗪类...出现在哺乳母亲的乳汁中。/噻嗪类/
  • Hazard categories and classifications: 急性毒性 4 (100%)
  • Non-fire leakage response: 储存注意事项:您应将此材料存放在冰箱中。(NTP, 1992)
  • Personal protective equipment (PPE): 推荐呼吸器:在称量和稀释纯测试化学品时,佩戴NIOSH批准的半面罩呼吸器,配备有机蒸气/酸性气体 cartridges(专门用于有机蒸气、HCl、酸性气体和SO2)和粉尘/雾过滤器。(NTP,1992)
  • Antidote and first aid: 噻嗪类利尿剂过量应立即进行胃排空,然后进行支持性对症治疗,并监测血清电解质浓度和肾功能。/噻嗪类利尿剂/
  • Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2019.09.022
  • Effects During Pregnancy and Lactation: 产后开始24小时内给予多噻嗪2mg,每日两次,持续8天,以抑制产后泌乳。患者还至少进行了10天的乳房束缚和液体限制。作者报告说,在审查的124个病例中,这种技术是有效的。关于利尿剂对已建立的泌乳的影响没有数据。
Related
upstream information
Manufacturing method:
乙二醇二甲醚(CID:8071);2,2,2-三氟乙醇(CID:6409);巯基乙醛(CID:77775)
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Research chemical 1mg

Research chemical 1mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 1mg.

item number:P343276-1mg
Product model:1mg
level: 1mg
Lead Time:-
sold 950 Items
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