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Product introduction
PD173074是脲类化合物的一种,是在1-叔丁基脲中,连接到N3的一个氢被吡啶并[2,3-d]嘧啶-7-基取代,该基团本身在2位和6位分别被4-(二乙氨基)丁基]氨基和3,5-二甲氧基苯基取代。它是FGF/VEGF受体酪氨酸激酶抑制剂。它具有抗肿瘤药物、EC 2.7.10.1(受体蛋白-酪氨酸激酶)抑制剂和成纤维细胞生长因子受体拮抗剂的作用。它是一种芳香胺、吡啶并嘧啶、脲类化合物、叔胺化合物、二甲氧基苯和联芳基化合物。它与PD-166866功能相关。
Chinese name
PD173074,FGFR1和FGFR3抑制剂
English name
1-tert-butyl-3-[2-[4-(diethylamino)butylamino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]urea
Chinese alias
-
English alias
A25450 | SMR000568412 | BCPP000121 | MFCD08705327 | CHEBI:63448 | HMS2233G17 | NSC766908 | NSC-766908 | UNII-A4TLL8634Y | 1-tert-Butyl-3-(6-(3,5-dimethoxyphenyl)-2-(4-diethylaminobutylamino)pyrido(2,3-d)pyrimidin-7-yl)urea | 2fgi | BDBM6190 | NCGC00165863
CAS number
219580-11-7
molecular formula
C28H41N7O3
molecular weight
523.7
Exact mass
-
PSA
114
Logp
4.5
Safety
  • Hazard categories and classifications: 特定靶器官毒性-单次接触 3 (97.4%)
Technical Documents
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PD173074 10mM in DMSO 1ml

PD173074 10mM in DMSO 1ml; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 1ml.

item number:P408061-1ml
Product model:1ml
level: 1ml
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