Share to
Overview
Specs
Safety
Technical Documents
Related
Articles
reviews
Consult
returns
Product introduction
哌唑嗪是哌嗪类化合物,是在1位被呋喃-2-甲酰基取代、在4位被4-氨基-6,7-二甲氧基喹唑啉-2-基取代的哌嗪。它具有降压药、α-肾上腺素能拮抗剂和EC 3.4.21.26(脯氨酸寡肽酶)抑制剂的作用。它是呋喃类、哌嗪类、一元羧酸酰胺、芳香醚和喹唑啉类的成员。
Chinese name
哌唑嗪, α 1A 肾上腺素受体拮抗剂
English name
[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone
Chinese alias
-
English alias
prazosin | 19216-56-9 | Furazosin | Prazosine | Prazosinum | Prazosina | Prazocin | Prazosine [INN-French] | Prazosinum [INN-Latin] | Prazosina [INN-Spanish] | [3H]-Prazosin | 2-(4-(2-Furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline | 1-(4-Amino-6,
CAS number
19216-56-9
molecular formula
C19H21N5O4
molecular weight
383.4
Exact mass
-
PSA
107
Logp
2
Safety
  • Harmful effect: 阳痿和阴茎异常勃起
  • Toxicity summary: 文献报道了一例儿科患者过量服用哌唑嗪导致低血压的病例,该病例对容量复苏、肾上腺素和去甲肾上腺素支持无反应。该患者同时服用了萘普生和对乙酰氨基酚。考虑到对乙酰氨基酚和哌唑嗪都在肝脏代谢,这可能导致药物清除时间延长。该患者对加压素有反应。
  • Hepatotoxicity: 可能性评分:E*(尚未证实但怀疑是引起明显肝损伤的罕见原因)。
  • Other safety information: 化学品评估:IMAP评估 - 哌嗪,1-(4-氨基-6,7-二甲氧基-2-喹唑啉基)-4-(2-呋喃甲酰基)-:人类健康I级评估
  • Hazard categories and classifications: 特定靶器官毒性-单次接触 3级 (50%)
  • Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2019.09.022
  • Effects During Pregnancy and Lactation: 截至修订日期,未在哺乳期妇女中找到相关已发表信息。哌唑嗪不影响高血压患者的血清催乳素浓度。已建立泌乳的母亲的催乳素水平可能不会影响她母乳喂养的能力。
Technical Documents
「No technical documents」
Related
「No upstream and downstream information yet」
Articles
「No related articles yet」
user reviews
Loading...
Consultation

Warm reminder:

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.!

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ,We will handle it for you as soon as possible, thank you for your support and trust.!

Research chemical 1ml

Research chemical 1ml; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 1ml.

item number:P422350-1ml
Product model:1ml
level: 1ml
Lead Time:30days
sold 98 Items
Ask Solution engineer
Specifications:

1ml

Qty

Recommended for you