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Product introduction

PCI 29732 是一种有效的可逆 BTK 抑制剂，对 BTK、Lck 和 Lyn 的 Kiapp 值分别为 8.2、4.6 和 2.5 nM。PCI 29732 对另一种 Tec 家族激酶 Itk 仅有适度的抑制活性。PCI 29732 通过竞争性结合ABCG2 的 ATP 结合位点来抑制 ABCG2 的功能。

Specs ⸢ View details ⸥

Chinese name

PCI 29732

English name

PCI 29732

Chinese alias

1-环戊基-3-(4-苯氧基苯基)-1H-吡唑并[3,4-d]嘧啶-4-胺

English alias

330786-25-9 | PCI 29732 | PCI-29732 | 1-Cyclopentyl-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | CHEMBL2057912 | PCI29732 | 4-amino-1-cyclopentyl-3-(4-phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidine | 1-cyclopentyl-3-(4-phenoxyphenyl)pyrazolo[3,4

CAS number

330786-25-9

molecular formula

C22H21N5O

molecular weight

371.44 g/mol

Exact mass

10mM in DMSO

PSA

78.900 Å²

Logp

4.200

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