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Product introduction

PNU-282987 (free base) 是一种有效的 α7 烟碱乙酰胆碱受体 (nAChR) 激动剂，EC50 为 154 nM。 PNU-282987 (free base) 也是 5-HT3 受体的功能性拮抗剂，IC50 为 4541 nM。PNU-282987 (free base) 可用于中枢和外周神经系统的研究。 Product description： PNU-282987 (free base) is a potent α7 nicotinic acetylcholine receptor (nAChR) agonist with an EC50 of 154 nM. PNU-282987 (free base) is also a functional antagonist of the 5-HT3 receptor with an IC50 of 4541 nM. PNU-282987 (free base) can be used for the research of central and peripheral nervous systems.

Specs ⸢ View details ⸥

Chinese name

PNU 282987, 烟碱乙酰胆碱受体 α7 亚基的激动剂

English name

PNU 282987

Chinese alias

N-(3R)-1-氮杂双环[2.2.2] oct-3-yl-4-chlorobenzamide

English alias

AKOS016339643 | PNU-282987 (free base) | PNU282987.HCl | EX-A3238 | PNU282987 | PNU-282987 | HMS3677E04 | MFCD08703110 | P2774 | AC-35375 | BDBM50161764 | HY-12560 | BCP0726000208 | BDBM50161753 | BRD-K28863208-001-01-2 | J-004946 | (R)-4-Chloro-N-(quinuc

CAS number

711085-63-1

molecular formula

C14H17ClN2O

molecular weight

264.75 g/mol

Exact mass

PSA

32.299 Å²

Logp

2.400

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