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Product introduction

应用使用吡那地尔：通过注入左前降支用于复极化研究在心室肌细胞中诱导ATP敏感性K+ (KATP)电流，用于电生理检查作为KATP开启剂来治疗心肌细胞 Pinacidil is a K+ channel opener. Pinacidil is demonstrated to induce relaxation of serotonin-produced contractions in porcine and human arterial rings. This action is suppressed by the ATP-dependent K+ (KATP) channel blockers Glibenclamide and Tetrapentylammonium salts, suggesting that relaxations induced by Pinacidil are mediated by opening of KATP channels. A K+ channel activator; antihypertensive Application Use pinacidil: Repolarization study by injection of left anterior descending branch Induction of ATP sensitive K + (KATP) currents in ventricular myocytes for electrophysiological examination As a KATP opener to treat cardiomyocytes

Specs ⸢ View details ⸥

Chinese name

吡那地尔一水合物, 磺酰脲受体 2，Kir6.2 开端

English name

Pinacidil monohydrate

Chinese alias

(±)-N-氰基-N'-4-吡啶-N″-(1,2,2-三甲基丙基)胍一水合物

English alias

CAS number

85371-64-8

molecular formula

C13H19N5 · H2O

molecular weight

263.34 g/mol

Exact mass

≥98%

PSA

74.100 Å²

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