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Product details

名称

p38α inhibitor 1, MAP 激酶 p38 alpha 抑制剂

分子类型

小分子

别名

p38α 抑制剂 1

英文别名

英文名称

p38α inhibitor 1

货号

P646474-5mg

包装规格

5mg

浓度

≥98%

储存温度

-20°C储存

运输条件

超低温冰袋运输

产品介绍

p38α inhibitor 1 is a p38α inhibitor extracted from patent WO 2008076265 A1. Form:Solid IC50& Target:p38α

生化机理

p38α 抑制剂 1 是一种提取自专利 WO 2008076265 A1 的 p38α 抑制剂。

CAS号

1034189-82-6

分子式

C22H26F2N4O2

分子量

416.46 g/mol

EC号

835-457-2

PubChem编号

46883775

Isomeric SMILES

CC(C)CN1C2=CC(=C(C=C2C=N1)OC3=C(C=C(C=C3)F)F)C(=O)NCCN(C)C

IIUPAC Name

5-(2,4-difluorophenoxy)-N-[2-(dimethylamino)ethyl]-1-(2-methylpropyl)indazole-6-carboxamide

INCHI

1S/C22H26F2N4O2/c1-14(2)13-28-19-11-17(22(29)25-7-8-27(3)4)21(9-15(19)12-26-28)30-20-6-5-16(23)10-18(20)24/h5-6,9-12,14H,7-8,13H2,1-4H3,(H,25,29)

InChi Key

IFGWYHGYNVGVRB-UHFFFAOYSA-N

Smiles

CC(C)CN1C2=CC(=C(C=C2C=N1)OC3=C(C=C(C=C3)F)F)C(=O)NCCN(C)C

PubChem CID

46883775

关联CAS

1036404-17-7

MeSH Entry Terms

ARRY-371797;ARRY-797

溶解性

DMSO : ≥ 125 mg/mL (300.15 mM)

氢键供体数Hydrogen Bond Donor Count

氢键受体数Hydrogen Bond Acceptor Count

可旋转键计数Rotatable Bond Count

精确质量Exact Mass

416.202 Da

单同位素质量Monoisotopic Mass

416.202 Da

拓扑极表面积Topological Polar Surface Area

59.400 Å²

重原子数Heavy Atom Count

形式电荷Formal Charge

复杂度Complexity

565

同位素原子数Isotope Atom Count

共价键合单元计数Covalently-Bonded Unit Count

XLogP3

3.9

ALogP

3.9

作用类型

抑制剂

作用机制

MAP 激酶 p38 alpha 抑制剂

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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