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Product introduction

PF-05381941 is a potent dual inhibitor of TAK1/p38α , with IC 50 s of 156 and186 nM, respectively In Vitro PF-05381941 inhibits LPS-stimulated release of TNF-αfrom human peripheralmononuclear (PMN) cells with an IC 50 of 8 nM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:p38α 186 nM (IC 50 ) TAK1 156 nM (IC 50 )

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Chinese name

PF-05381941

English name

PF-05381941

Chinese alias

English alias

CAS number

1474022-02-0

molecular formula

C27H26N6O2

molecular weight

466.53 g/mol

Exact mass

≥99%

PSA

Logp

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